Determination of Menadione Sodium Bisulfite in Pharmaceutical Preparations by Flow-Injection On-line Photochemical Spectrofluorometry
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منابع مشابه
Determination of menadione sodium bisulfite in pharmaceutical preparations by flow-injection on-line photochemical spectrofluorometry.
A flow-injection on-line photochemical spectrofluorometry (FI-PF) was developed for the determination of menadione sodium bisulfite (MSB) using acetone and sodium sulfite as sensitizing reagents. An injected sample band carried by a water stream was on-line merged with a mixed NaOH, Na2SO3 and acetone solution in a "T" connector. It was then driven to pass a knotted PTFE photochemical reactor (...
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Firstand second-order derivative spectrophotometric methods for the quantitative determination by converting menadione sodium bisulphite (MSB) to menadione (M ) with sodium carbonate were developed and validated in pharmaceutical preparation. The quantitative determination of MSB was carried out by using wavelengths 350 nm (for first-order; 1D) and 355 nm (for second-order; 2D) with the lineari...
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GC-FID and HPLC-DAD were developed for determination of menadione (MN) and menadione sodium bisulphite (MSB). By means of each method, quantitative analysis of MSB in commercial pharmaceutical was performed in both direct analysis of MSB and analysis of MN by converting MSB to MN with sodium carbonate. GC-FID method was carried out on the HP-5 capillary column using nitrogen gas. HPLC-DAD metho...
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ژورنال
عنوان ژورنال: Analytical Sciences
سال: 2001
ISSN: 0910-6340,1348-2246
DOI: 10.2116/analsci.17.1209